2017. július 18., kedd

Az élet-energia raktára

When a cell or organism has more than enough metabolic fuel available to meet its energetic needs, the excess is generally converted to fatty acids and stored as lipids such as triacylglycerols. The reaction catalyzed by acetyl-CoA carboxylase is the rate-limiting step in the biosynthesis of fatty acids, and this enzyme is an important site of regulation. In vertebrates, palmitoyl-CoA, the principal product of fatty acid synthesis, acts as a feedback inhibitor of the enzyme, and citrate is an allosteric activator (Fig. 20-12a)

Lehninger-Nelson-Cox: Principles of Biochemistry, 652.o. 

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Szószedet: homeostasis (önbévület*)

homeostasis : The maintenance of a dynamic steady state by regulatory mechanisms that compensate for changes in external circumstances. ___...