2017. július 19., szerda

Hoppsz: linoleátot és linolenátot sem tudunk gyártani !

Linoleate, 18:2(Δ9,12), and α-linolenate, 18:3(Δ9,12,15, cannot be synthesized by mammals, but plants can synthesize both. The plant desaturases that introduce double bonds at Δ12 and Δ15 positions are located in the endoplasmic reticulum. These enzymes act not on free fatty acids but on a phospholipid, phosphatidylcholine, containing at least one oleate linked to glycerol (Fig. 20-15, p. 656).
Because they are necessary precursors for the synthesis of other products, linoleate and linolenate are essential fatty acids for mammals; they must be obtained from plant material in the diet.

Lehninger-Nelson-Cox: Principles of Biochemistry, 655.o. 

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