2017. augusztus 16., szerda

De, ha a vírus belénk oltja a programhibát - abból lesz: a rák !

Many viral oncogenes encode unregulated tyrosine kinase activities, and in some cases the oncogene product is nearly identical to a normal animal-cell receptor, but with the normal signal-binding site defective or missing. For example, the erbB oncogene product, a protein called ErbB, is essentially identical to the normal receptor for epidermal growth factor, except that ErbB lacks the domain that normally binds EGF (Fig. 22-37, p. 777). The erbB2 oncogene is commonly associated with adenocarcinomas (cancers) of the breast, stomach, and ovary.

Lehninger-Nelson-Cox: Principles of Biochemistry, 776.o.

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Szószedet: homeostasis (önbévület*)

homeostasis : The maintenance of a dynamic steady state by regulatory mechanisms that compensate for changes in external circumstances. ___...