2017. június 14., szerda

Védve vagyunk önemésztés ellen

... Synthesis of these enzymes as inactive precursors protects the exocrine cells from destructive proteolytic attack.
The pancreas protects itself against self-digestion in another way - by making a specific inhibitor, itself a protein, called pancreatic trypsin inhibitor (p. 235).
Free trypsin can activate not only trypsinogen but also three other digestive zymogens: chymotrypsinogen, procarboxypeptidase, and proelastase; trypsin inhibitor effectively prevents premature production of free proteolytic enzymes within the pancreatic cells.

Lehninger-Nelson-Cox: Principles of Biochemistry, 510.o.

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Szószedet: homeostasis (önbévület*)

homeostasis : The maintenance of a dynamic steady state by regulatory mechanisms that compensate for changes in external circumstances. ___...